Computational Medicine (Record no. 103922)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 04517nam a22004695i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-7091-0947-2 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220083332.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120918s2012 au | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783709109472 |
| -- | 978-3-7091-0947-2 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-7091-0947-2 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH506 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MBGR |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSD |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI049000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED067000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 611.01816 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Trajanoski, Zlatko. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Computational Medicine |
| Medium | [electronic resource] : |
| Remainder of title | Tools and Challenges / |
| Statement of responsibility, etc | edited by Zlatko Trajanoski. |
| 264 #1 - | |
| -- | Vienna : |
| -- | Springer Vienna : |
| -- | Imprint: Springer, |
| -- | 2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | IX, 203 p. 25 illus., 19 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. Bioinformatics tools for the search of disease-associated variations. Stefan Coassin, Anita Kloss-Brandstätter, Florian Kronenberg -- 2. Cloud computing: bringing computational power to medical genetics. Lukas Forer, Sebastian Schönherr, Hansi Weißensteiner, Günther Specht, Florian Kronenberg, Anita Kloss-Brandstätter -- 3. High-throughput characterization and comparison of microbial communities. Bettina Halwachs, Gregor Gorkiewicz, Gerhard G. Thallinger -- 4. Microarray Meta-Analysis: From Data to Expression to Biological Relationships. Julia Feichtinger, Gerhard G. Thallinger, Ramsay J. McFarlane, Lee Larcombe -- 5. Analysis of labeled quantitative mass spectrometry proteomics data. Florian Breitwieser, Jacques Colinge -- 6. Lipidomics, Mass Spectrometry and Bioinformatics. Jürgen Hartler, Harald C. Köfeler, Christopher J.O. Baker, Ravi Tharakan, Gerhard G. Thallinger -- 7. Protein sequence-structure-function-network links discoveries with the ANNOTATOR software suite: Application to ELYS/Mel-28analysis. Georg Schneider, Westley Sherman, Durga Kuchibhatla, Ooi Hong Sain, Fernanda L. Sirota, Sebastian Maurer-Stroh, Birgit Eisenhaber, Frank Eisenhaber -- 8. 3D structure and drug design. Kristina Djinovic-Carugo, Oliviero Carugo -- 9. Integrating biomolecular and clinical data for cancer research: concepts and challenges. Pornpimol Charoentong, Hubert Hackl, Bernhard Mlecnik, Gabriela Bindea, Jerome Galon, Zlatko Trajanoski -- 10. Applied data mining: from biomarker discovery to decision support systems. Melanie Osl, Michael Netzer, S. Dreiseitl, Christian Baumgartner -- 11. Network-based methods for computational diagnostics by means of R. Laurin A.J. Müller, Mathias Dehmer, Frank Emmert-Streib. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically addressing medical problems. In this book, we present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Bioinformatics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cytology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Molecular Medicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Bioinformatics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cell Biology. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783709109465 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-7091-0947-2 |
| 912 ## - | |
| -- | ZDB-2-SBL |
No items available.