Cytoskeleton and Human Disease (Record no. 101617)

000 -LEADER
fixed length control field 03428nam a22004935i 4500
001 - CONTROL NUMBER
control field 978-1-61779-788-0
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083252.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120420s2012 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781617797880
-- 978-1-61779-788-0
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-61779-788-0
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH573-671
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSF
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI049000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 571.6
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Kavallaris, Maria.
Relator term editor.
245 10 - TITLE STATEMENT
Title Cytoskeleton and Human Disease
Medium [electronic resource] /
Statement of responsibility, etc edited by Maria Kavallaris.
264 #1 -
-- Totowa, NJ :
-- Humana Press :
-- Imprint: Humana Press,
-- 2012.
300 ## - PHYSICAL DESCRIPTION
Extent XXIV, 453p. 63 illus., 42 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Actin -- Microtubules -- The Kinesin Superfamily -- Myosins -- The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes -- Thin Filament Disease of Stricted Muscle -- Filamin and disease -- LIMK and Cancer Metastasis -- Actin Mutations and Deafness -- Therapeutic Targeting of the Actin Cytoskeleton -- Microtubules as a Target in Cancer Therapy -- Microtubules and drug resistance -- Posttranslational Modifications of Tubulin -- Stathmin and Cancer -- The Biology and Pathobiology of Tau Protein -- Tubulin-Related Malformations of Cortical Development -- Spectrins in Human Diseases -- Laminopathies -- Desmin and Heart Disease -- Neurodegenerative Diseases and Intermediate Filaments.
520 ## - SUMMARY, ETC.
Summary, etc The cytoskeleton is made up of a large variety of specialized proteins and is a highly dynamic system that is involved in the majority of key cellular events. It is now clear that the cytoskeleton is often associated, and has diverse roles in human disease.  Emerging understanding of the molecular and cellular events that drive cytoskeletal mediated disease including cancer, heart disease, myopathies, neurodegenerative diseases and skin disorders, are also helping shape targeted therapeutic approaches to treat these diseases.   Cytoskeleton and Human Disease Book Summary reviews the key components, mechanisms and clinical implications of cytoskeletal defects in disease. Contributed by leading investigators in their respective fields, the chapters include topics associated with the basics of the cytoskeleton, actin-associated disease states, microtubule-associated disease states and intermediate filament-associated disease states.   This authoritative volume is intended for a wide audience of clinicians, researchers and students with an interest in the application of biomedical research to the understanding and management of disease states associated with the cytoskeleton.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life sciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oncology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cytology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cell cycle.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life Sciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cell Biology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cell Cycle Analysis.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cell Physiology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry, general.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer Research.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781617797873
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-61779-788-0
912 ## -
-- ZDB-2-SBL

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