Antibiotic Discovery and Development (Record no. 101059)

000 -LEADER
fixed length control field 03109nam a22004815i 4500
001 - CONTROL NUMBER
control field 978-1-4614-1400-1
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083242.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 111217s2012 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461414001
-- 978-1-4614-1400-1
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4614-1400-1
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QR46
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMFM
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED052000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.9041
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Dougherty, Thomas J.
Relator term editor.
245 10 - TITLE STATEMENT
Title Antibiotic Discovery and Development
Medium [electronic resource] /
Statement of responsibility, etc edited by Thomas J. Dougherty, Michael J. Pucci.
264 #1 -
-- Boston, MA :
-- Springer US,
-- 2012.
300 ## - PHYSICAL DESCRIPTION
Extent XVII, 1127p. 211 illus., 80 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Introductory History of Antimicrobial Drugs -- Marketed Major Classes of Compounds -- The Rise of Antibiotic Resistance/Resistance Mechanisms to Major Classes -- Clinical Issues of Resistance: “Worst Offenders” List of Problematic Microbes -- Antibiotic Discovery -- Antibiotic Drug Development -- The Economics and Incentives of Antibiotic Drug Discovery.
520 ## - SUMMARY, ETC.
Summary, etc This volume covers major aspects of the antibiotic discovery and development process. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the historical perspectives of antibiotic discovery, the need for new antibiotic compounds,strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Significant attention is given to existing antibiotics, their resistance mechanisms, and new efforts to overcome resistance within these classes.  Beyond discovery, the book covers the studies to prepare for IND submission and NDA filings. This book walks the reader through virtually all aspects of antibiotic discovery, which has never been done before in a single reference. With the alarming rise in antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the book is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Microbiology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Toxicology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Chemistry, Physical organic.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medical Microbiology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmacology/Toxicology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Physical Chemistry.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Molecular Medicine.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pucci, Michael J.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781461413998
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4614-1400-1
912 ## -
-- ZDB-2-SBL

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