Mitochondrial Dysfunction in Neurodegenerative Disorders (Record no. 100270)

000 -LEADER
fixed length control field 03861nam a22005175i 4500
001 - CONTROL NUMBER
control field 978-0-85729-701-3
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083228.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 111114s2012 xxk| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780857297013
-- 978-0-85729-701-3
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-0-85729-701-3
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC346-429.2
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJN
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED056000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.8
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Reeve, Amy Katherine.
Relator term editor.
245 10 - TITLE STATEMENT
Title Mitochondrial Dysfunction in Neurodegenerative Disorders
Medium [electronic resource] /
Statement of responsibility, etc edited by Amy Katherine Reeve, Kim Jennifer Krishnan, Michael R. Duchen, Doug M Turnbull.
264 #1 -
-- London :
-- Springer London :
-- Imprint: Springer,
-- 2012.
300 ## - PHYSICAL DESCRIPTION
Extent XXI, 242p. 20 illus., 12 illus. in color.
Other physical details online resource.
336 ## -
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-- txt
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337 ## -
-- computer
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338 ## -
-- online resource
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347 ## -
-- text file
-- PDF
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505 0# - FORMATTED CONTENTS NOTE
Formatted contents note An Introduction to Mitochondria -- Neurodegeneration in Primary Mitochondrial Disorders -- Mutations in Nuclear Genes that Affect Mitochondrial Function in Parkinson’s Disease -- Common mtDNA Polymorphisms and Neurodegenerative Disorders -- MtDNA Mutations in Brain Ageing and Neurodegeneration -- Mitochondrial Dysfunction in Neurodegenerative Disease; Protein Aggregation, Autophagy and Oxidative Stress -- Mitochondria, Sodium and Calcium in Neuronal Dysfunction -- Mitochondrial Membrane Potential and Dynamics -- Dysfunction of the Ubiquitin/Proteasome System and Mitochondria in Neurodegenerative Disease -- Neuronal Mitochondrial Transport and Dysfunction -- Mitochondrial Changes Associated With Demyelination: Consequences for Axonal Integrity -- Modelling Mitochondrial Dysfunction in Neurodegenerative Disease -- Could Understanding the Role Of Mitochondria in Neurodegeneration Lead to Treatment?.
520 ## - SUMMARY, ETC.
Summary, etc As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration.   Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets.   Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurosciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Internal medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medical Biochemistry.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurosciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Internal Medicine.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Krishnan, Kim Jennifer.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Duchen, Michael R.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Turnbull, Doug M.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9780857297006
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-0-85729-701-3
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